The Antidepressant Effects of Domestic Natural Mixed Fragrance Ingredients in Animal Models

Background: This study used inhalation toxicity experiments, open field and tail suspension tests to investigate the antidepressant effect of a combination nine types refined oils extracted from domestic native plants.Methods: Non-irritability was confirmed through an test, locomotor activity measured using assessed by measuring immobility time during test.Results: The test that both samples were non-stimulated with negative stimulation index 0.0. In experiment, floating significantly shorter than depression model, average 142.33±18.31 seconds compared control group at 0.5% concentration (F=10.582, p＜.001).Conclusions: study’s results suggest combining plants could be develop prototypes effectively alleviate depression. Future studies should include usability evaluation human application further these potential benefits.